University Breast Center Heidelberg, Heidelberg, Germany.
Ann Surg Oncol. 2011 Aug;18(8):2143-9. doi: 10.1245/s10434-011-1565-y. Epub 2011 Feb 3.
We evaluated whether a supplementary preoperative breast MRI in patients with invasive lobular breast cancer (ILC) has changed number and methods of primary and number of secondary surgical interventions.
This was a retrospective controlled single-center analysis of 178 ILC patients. The 2 study groups consisted of 92 patients with breast MRI (MRI group) and of 86 patients without breast MRI (non-MRI group). We investigated the primary and final surgical procedures and factors that influenced the number of secondary surgical interventions.
A total of 40 primary mastectomies (38%) have been performed in the MRI group, compared with 27 (30%) in the non-MRI group (P = .119).There have been more bilateral surgical interventions in the MRI group (14 vs 3 patients; P = .002). The 2 groups did not differ with respect to secondary surgery rates (P = .429). The MRI and non-MRI group were significantly different with respect to age and breast density (P = .003 and P = .002). Yet, both variables seemed not to influence secondary surgery rates (P = .516 and P = .788, respectively).
The implementation of preoperative breast MRI tended to result in more primary mastectomies and bilateral surgeries and did not seem to decrease the secondary surgery rate.
我们评估了浸润性小叶乳腺癌（ILC）患者补充术前乳腺 MRI 是否改变了主要手术和次要手术的数量和方法。
这是一项回顾性对照单中心分析了 178 例 ILC 患者。2 个研究组由 92 例有乳腺 MRI（MRI 组）和 86 例无乳腺 MRI（非 MRI 组）的患者组成。我们研究了主要和最终的手术程序以及影响次要手术数量的因素。
MRI 组共行 40 例全乳切除术（38%），而非 MRI 组为 27 例（30%）（P =.119）。MRI 组有更多的双侧手术干预（14 例与 3 例；P =.002）。两组在继发性手术率方面无差异（P =.429）。MRI 组和非 MRI 组在年龄和乳腺密度方面存在显著差异（P =.003 和 P =.002）。然而，这两个变量似乎都不影响继发性手术率（P =.516 和 P =.788，分别）。
术前乳腺 MRI 的实施倾向于导致更多的全乳切除术和双侧手术，且似乎并未降低继发性手术率。
