Department of Chemistry, Wayne State University, Detroit, MI 48202, USA.
J Sep Sci. 2011 Apr;34(8):888-900. doi: 10.1002/jssc.201000724. Epub 2011 Feb 2.
This article provides a summary of the development of ionic liquids as stationary phases for gas chromatography beginning with early work on packed columns that established details of the retention mechanism and established working methods to characterize selectivity differences compared with molecular stationary phases through the modern development of multi-centered cation and cross-linked ionic liquids for high-temperature applications in capillary gas chromatography. Since there are many reviews on ionic liquids dealing with all aspects of their chemical and physical properties, the emphasis in this article is placed on the role of gas chromatography played in the design of ionic liquids of low melting point, high thermal stability, high viscosity, and variable selectivity for separations. Ionic liquids provide unprecedented opportunities for extending the selectivity range and temperature-operating range of columns for gas chromatography, an area of separation science that has otherwise been almost stagnant for over a decade.
本文综述了离子液体作为气相色谱固定相的发展，从早期的填充柱工作开始，该工作确定了保留机制的细节，并通过现代多中心阳离子和交联离子液体的发展，建立了工作方法，以表征与分子固定相相比的选择性差异，这些离子液体适用于毛细管气相色谱中的高温应用。由于有许多关于离子液体的综述涉及它们的化学和物理性质的各个方面，因此本文的重点是气相色谱在设计低熔点、高热稳定性、高粘度和可变选择性分离的离子液体方面所起的作用。离子液体为扩展气相色谱柱的选择性范围和温度操作范围提供了前所未有的机会，而这一分离科学领域在过去十年中几乎停滞不前。
