Boreskov Institute of catalysis SB RAS, pr. Lavrentieva 5, Novosibirsk 630090, Russia.
J Chromatogr A. 2013 Sep 27;1309:56-63. doi: 10.1016/j.chroma.2013.08.030. Epub 2013 Aug 13.
Recent advances in the development of new liquid phases (ILs) made it possible to use some classes of ILs as polar stationary liquid phases (SLP). In our days only alkylimidazolium- and alkylphosphonium-based ILs are widely used as polar SLP. In present work some other types of ILs - pyridinium and cyanopropyl/hydroxypropyl imidazolium were investigated as SLP. Columns with efficiencies 2000-2500 plates/m by high-pressure static method were prepared. Polarity and selectivity of these phases were measured. Selectivity was described in terms of intermolecular interactions by using Abraham solvatation parameter model. The set of the regularities between cation structure of ionic liquid and selectivity has been shown. The number and position of methyl groups in ionic liquid pyridinium ring were shown to have the sufficient influence on all type of molecular interactions. Finally the resolutions of test mixture for the several ionic liquid SLP were obtained. For columns with some ionic liquids the dependencies of the height equivalent to a theoretical plate (HETP) and sample loading capacity were obtained and compared with the conventional phases. It was found that the optimal efficiency for the IL columns is attained at lower carrier gas velocities in comparison with traditional phases. Nevetheless sample loading capacity of IL phases is comparable to those of conventional GC phases.
近年来，新型液相（ILs）的发展取得了进展，使得某些类别的 ILs 可以用作极性固定液相（SLP）。如今，烷基咪唑鎓和烷基膦鎓基 ILs 被广泛用作极性 SLP。在本工作中，还研究了其他类型的 ILs-吡啶鎓和氰丙基/羟丙基咪唑鎓作为 SLP。通过高压静态法制备了效率为 2000-2500 板/m 的色谱柱。测量了这些相的极性和选择性。使用 Abraham 溶剂化参数模型，根据分子间相互作用来描述选择性。展示了离子液体阳离子结构与选择性之间的规律之间的关系。离子液体吡啶环中阳离子的甲基数目和位置对所有类型的分子相互作用都有足够的影响。最后，获得了几种离子液体 SLP 测试混合物的分辨率。对于一些离子液体的色谱柱，获得了高度等效理论板（HETP）和样品负载容量的依赖性，并与传统相进行了比较。结果表明，与传统相相比，IL 柱的最佳效率在较低的载气流速下达到。尽管如此，IL 相的样品负载容量与传统 GC 相相当。
