Karaman A
Department of Medical Genetics, Erzurum Nenehatun Obstetrics and Gynecology Hospital, Erzurum, Turkey.
Genet Couns. 2010;21(4):385-95.
Down syndrome (DS) is diagnosed in approximately 1 Per 800 live births and is the most common known genetic cause of medical problems. To determine the prevalence of common medical problems in children with DS, a study was conducted between December 2003 and March 2010 in the Erzurum Nenehatun Obstetrics and Gynecology Hospital. 107 children with DS were entered into a retrospective observational study. Case notes were reviewed to obtain details regarding complications of children with DS. Medical problems such as cardiac, gastrointestinal, respiratory, sensory, orthopaedic anomalies, endocrine disorders, and obesity occur more frequently in children with DS. Clinicians should be aware of the risk of problems in children with DS.
唐氏综合征（DS）在每800例活产中约有1例被诊断出来，是已知最常见的导致医学问题的遗传原因。为了确定唐氏综合征患儿常见医学问题的患病率，2003年12月至2010年3月在埃尔祖鲁姆内内哈通妇产科医院进行了一项研究。107例唐氏综合征患儿纳入回顾性观察研究。查阅病历以获取有关唐氏综合征患儿并发症的详细信息。心脏、胃肠道、呼吸、感官、骨科异常、内分泌失调和肥胖等医学问题在唐氏综合征患儿中更频繁出现。临床医生应意识到唐氏综合征患儿出现问题的风险。
