[人类多巴胺能D3受体的基因克隆及其染色体定位]
[Gene cloning of human dopaminergic D3 receptor and identification of its chromosome].
作者信息
Giros B, Martres M P, Sokoloff P, Schwartz J C
机构信息
Unité de Neurobiologie et Pharmacologie (U.n. 109) de l'I.N.S.E.R.M., Centre Paul-Broca, Paris.
出版信息
C R Acad Sci III. 1990;311(13):501-8.
PMID:2129115
Abstract
The coding region of the human dopaminergic D3 receptor gene was cloned and sequenced. The deduced amino acid sequence displays a global homology of 78% with rat D3 receptor with a deletion of 46 residues within the third intracytoplasmic loop. Southern analysis assigned the human gene to chromosome 3.
摘要
克隆并测序了人类多巴胺能D3受体基因的编码区。推导的氨基酸序列与大鼠D3受体的整体同源性为78%，在第三个胞质内环中有46个残基的缺失。Southern分析将人类基因定位于3号染色体。
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