Yasumoto K, Shimada C, Hosoyamada A, Inada Y
Department of Anesthesiology, Showa University, Faculty of Medicine, Tokyo.
Masui. 1990 Dec;39(12):1602-6.
A comparative investigation into the functioning time of three brands of CO2 absorbents was performed. The three investigated brands were: Viosorb, Wakolime, and Wakolime-A. In this study PICO2 was measured to know the drug's functioning time and CO2 elimination from the model lung fixed at 200 or 300 ml.min-1. PICO2 was less than 1 mmHg for 34 to 55 hours at VCO2 of 200 ml. min-1 and for 32 to 48 hours at VCO2 of 300 ml.min-1. PICO2 increased exponentially in all CO2 absorbents. There were statistically significant relation between PICO2 and time. The CO2 absorbent whose shape is tablet has the longest functioning time because it could be placed smoothly in the canister. It is concluded that the shape of CO2 absorbent plays a role in determining its functioning time.
对三种品牌的二氧化碳吸收剂的作用时间进行了对比研究。所研究的三个品牌分别是：Viosorb、Wakolime和Wakolime - A。在本研究中，通过测量PICO2来了解药物的作用时间以及在固定为200或300 ml·min⁻¹的模拟肺中的二氧化碳清除情况。在VCO2为200 ml·min⁻¹时，PICO2在34至55小时内低于1 mmHg，在VCO2为300 ml·min⁻¹时，PICO2在32至48小时内低于1 mmHg。在所有二氧化碳吸收剂中，PICO2呈指数增长。PICO2与时间之间存在统计学上的显著关系。呈片剂形状的二氧化碳吸收剂作用时间最长，因为它可以顺利地放置在罐中。得出的结论是，二氧化碳吸收剂的形状在决定其作用时间方面发挥着作用。
