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苯环利定:来自纽约市法医办公室的5年回顾性研究。

Phencyclidine: a 5-year retrospective review from the New York City Medical Examiner's Office.

作者信息

deRoux Stephen J, Sgarlato Anthony, Marker Elizabeth

机构信息

New York City Office of Chief Medical Examiner and Department of Forensic Medicine, New York University School of Medicine, New York, NY 10016, USA.

出版信息

J Forensic Sci. 2011 May;56(3):656-9. doi: 10.1111/j.1556-4029.2010.01687.x. Epub 2011 Feb 3.

Abstract

We report here a 5-year retrospective review of autopsy cases from the New York City Medical Examiner's Office that demonstrated phencyclidine (PCP) in the blood. There were a total of 138 cases. There were 52 deaths because of mixed drug intoxication: the blood PCP concentrations in these cases ranged from <1 to 598 ng/mL. There were 80 violent deaths in which PCP was quantified in the blood but was unrelated to the cause of death. There were five nonviolent deaths in which PCP exclusively was detected. In four of these, there were preexisting medical conditions that could also have contributed to death. In these, the highest PCP concentration was 361.3 ng/mL, a concentration lower than seven of the individuals in our violent death category. This suggests that lower concentrations may be fatal with comorbid conditions.

摘要

我们在此报告对纽约市法医办公室尸检病例进行的为期5年的回顾性研究,这些病例血液中检测出苯环己哌啶(PCP)。总共有138例病例。52例死于混合药物中毒:这些病例血液中PCP浓度范围为<1至598 ng/mL。80例暴力死亡病例中,血液中检测到PCP,但与死因无关。5例非暴力死亡病例中仅检测到PCP。其中4例存在可能导致死亡的原有疾病。在这些病例中,PCP最高浓度为361.3 ng/mL,低于我们暴力死亡类别中的7个人的浓度。这表明在存在合并症的情况下,较低浓度也可能致命。

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