Department of Cardiovascular and Thoracic Surgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
J Thorac Cardiovasc Surg. 2011 Apr;141(4):917-25. doi: 10.1016/j.jtcvs.2010.12.006. Epub 2011 Feb 3.
Cusp prolapse causing aortic insufficiency is associated with unique echocardiographic, clinical, and surgical features. Recognition and appropriate surgical repair of this pathologic condition can not only treat affected patients but also improve results of aortic valve-sparing procedures, for which pre-existing or induced cusp prolapse is an important cause of failure.
Of 428 patients undergoing aortic valve repair, 195 (46%) were treated for cusp prolapse, and 111 (57%) of those had trileaflet aortic valve and make up this cohort. Cusp disease was the sole mechanism for aortic insufficiency (isolated group) in 50 patients whereas aortic dilatation was contributory in 61 (associated group). In total, 144 cusps were repaired in 111 patients. Preoperative echocardiograms, intraoperative findings, and clinical and echocardiographic outcomes were reviewed.
On preoperative echocardiography, presence of an eccentric aortic insufficiency jet, regardless of severity, had 92% sensitivity and 96% specificity for the detection of single cusp prolapse. A transverse fibrous band was characteristically identified on the prolapsing cusp (sensitivity 57%; specificity 92%), correctly localizing a prolapsing cusp in all cases. Freedom from aortic valve reoperation at 8 years was 100% in the isolated group and 93% ± 5% in the associated group (p = 0.33). Freedom from recurrent aortic insufficiency (>2+) at 5 years was 90% ± 5% in the isolated and 85% ± 8% in the associated group (P = .54). The choice of surgical technique did not affect aortic insufficiency recurrence at follow-up (P = .6).
Recognition and repair of isolated aortic cusp prolapse provides durable midterm outcome. An eccentric aortic insufficiency jet and a fibrous band can aid in the diagnosis and localization of cusp prolapse associated with ascending aortic disease and may help to improve results of aortic valve-sparing procedures.
瓣叶脱垂导致主动脉瓣关闭不全与独特的超声心动图、临床和手术特征相关。识别和适当的手术修复这种病理状况不仅可以治疗受影响的患者,还可以改善主动脉瓣保留手术的结果,而瓣叶脱垂是导致该手术失败的一个重要原因。
在 428 例行主动脉瓣修复的患者中,195 例(46%)因瓣叶脱垂而接受治疗,其中 111 例(57%)为三叶瓣主动脉瓣,并构成本队列。瓣叶疾病是 50 例患者主动脉瓣关闭不全的唯一机制(单纯组),而主动脉扩张在 61 例患者中是促成因素(相关组)。总共对 111 例患者的 144 个瓣叶进行了修复。回顾术前超声心动图、术中发现以及临床和超声心动图结果。
术前超声心动图上,无论严重程度如何,偏心性主动脉瓣关闭不全射流对单一瓣叶脱垂的检测具有 92%的敏感性和 96%的特异性。脱垂瓣叶上可特征性地识别出横向纤维带(敏感性 57%;特异性 92%),在所有病例中均正确定位脱垂瓣叶。单纯组的主动脉瓣再次手术 8 年无失败率为 100%,相关组为 93%±5%(p=0.33)。单纯组 5 年无复发性主动脉瓣关闭不全(>2+)的无失败率为 90%±5%,相关组为 85%±8%(P=0.54)。在随访期间,手术技术的选择并不影响主动脉瓣关闭不全的复发(P=0.6)。
识别和修复单纯性主动脉瓣叶脱垂可提供持久的中期结果。偏心性主动脉瓣关闭不全射流和纤维带有助于诊断和定位与升主动脉疾病相关的瓣叶脱垂,并可能有助于改善主动脉瓣保留手术的结果。