Carrier H, Guillaud-Barbaret C, Chazot G, Bady B, Schott B
Acta Neuropathol. 1978 Oct 13;44(1):77-81. doi: 10.1007/BF00691643.
Five cases of peripheral neuropathies occurring with monoclonal gammapathies are studied by means of nerve biopsies. Immunofluorescence and HRP-immunolabelling with the electron microscope are performed. The direct pathogenic role of a subperineurial immunoglobulin deposit is pointed out. The relationship of the heavy chain monoclonal immunoglobulin with amyloid fibrils is discussed.
通过神经活检对5例伴有单克隆丙种球蛋白病的周围神经病变进行了研究。采用免疫荧光法以及电子显微镜下的辣根过氧化物酶免疫标记法。指出了神经束膜下免疫球蛋白沉积的直接致病作用。讨论了重链单克隆免疫球蛋白与淀粉样原纤维的关系。