Masson R, Carrier H, Barbaret C, Boucher M, Chazot G, Peaud P Y, Revol L
Rev Neurol (Paris). 1977 Aug-Sep;133(8-9):475-84.
In two cases of peripheral neuropathy, associated with a chronic lymphopathy, cobalt therapy to the lower limbs provided considerable relief of pain, with partial motor recovery. The disappearance after cobalt therapy of the lymphoid infiltrate of the peripheral nerve leads to discussion of the pathogeni role of this infiltrate. Immunofluorescent and electron microscopic studies form the basis of a discussion of the mechanism of involvement of the peripheral nerve non-secreting lymphopathies (chronic lymphoid leukaemia) and in secreting lymphopathies (Waldenström's disease).
在两例伴有慢性淋巴病的周围神经病患者中,对下肢进行钴治疗可显著缓解疼痛,并伴有部分运动功能恢复。钴治疗后周围神经淋巴浸润消失,这引发了对该浸润致病作用的讨论。免疫荧光和电子显微镜研究为探讨非分泌性淋巴病(慢性淋巴细胞白血病)和分泌性淋巴病(瓦尔登斯特伦病)累及周围神经的机制奠定了基础。