University of North Carolina.
Blood. 2011 Feb 3;117(5):1442-3. doi: 10.1182/blood-2010-11-317230.
In this issue of Blood, Haling and colleagues demonstrate that in addition to talin-dependent integrin activation, talin is required for platelet fibrin clot retraction by physically linking integrins to the actin cytoskeleton.
在本期《Blood》中，Haling 及其同事证明，除了依赖于 talin 的整合素激活外，talin 通过将整合素物理连接到肌动蛋白细胞骨架来促进血小板纤维蛋白凝块回缩也是必需的。
