Department of Radiology, University of Pittsburgh Medical Center, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15224, USA.
AJNR Am J Neuroradiol. 2011 Apr;32(4):639-42. doi: 10.3174/ajnr.A2358. Epub 2011 Feb 3.
GBS and its MFS variant are acute polyneuropathies that are considered to represent a continuum rather than distinct entities, due to the overlap in their clinical features. Enhancement of the CE roots represents the neuroradiologic hallmark of GBS, while findings of neuroimaging studies in MFS are usually unremarkable. Our purpose was to evaluate the MR imaging findings of polyneuropathy in 17 children affected by GBS and its MFS variant. Fourteen of our 17 patients demonstrated CE enhancement, with predominant involvement of the anterior roots. Of 6 patients who underwent MR imaging of the brain, 5 had cranial nerve involvement. In children affected by GBS-MFS, involvement of the CE roots may be considered part of a more extensive autoimmune neuropathy, as demonstrated by enhancement of cranial nerves. Brain MR imaging should be considered in the routine evaluation in pediatric patients with GBS-MFS for the evaluation of the cranial nerves.
GBS 及其 MFS 变体都是急性多发性神经病，由于其临床特征重叠，被认为代表一个连续体而不是不同的实体。CE 根增强是 GBS 的神经放射学标志，而 MFS 神经影像学研究的结果通常无明显异常。我们的目的是评估 17 例 GBS 及其 MFS 变体患儿多发性神经病的磁共振成像表现。我们的 17 例患者中有 14 例表现出 CE 增强，主要累及前根。6 例行脑磁共振成像的患者中有 5 例有颅神经受累。在 GBS-MFS 患儿中，CE 根受累可被认为是更广泛自身免疫性神经病的一部分，这可通过颅神经增强来证明。对于 GBS-MFS 患儿，应考虑在常规评估中进行脑磁共振成像，以评估颅神经。
