Department of Anesthesiology and Reanimation, Faculty of Medicine and Pharmacy of Agadir, University Ibn Zohr, Agadir, Morocco.
Department of Radiology, Faculty of Medicine and Pharmacy of Agadir, University Ibn Zohr, Agadir, Morocco.
Pan Afr Med J. 2024 Mar 22;47:127. doi: 10.11604/pamj.2024.47.127.42985. eCollection 2024.
Guillain-Barré syndrome/Miller-Fisher syndrome (GBS/MFS) overlap syndrome is an extremely rare variant of Guillain-Barré syndrome (GBS) in which Miller-Fisher syndrome (MFS) coexists with other characteristics of GBS, such as limb weakness, paresthesia, and facial paralysis. We report the clinical case of a 12-year-old patient, with no pathological history, who acutely presents with ophthalmoplegia, areflexia, facial diplegia, and swallowing and phonation disorders, followed by progressive, descending, and symmetrical paresis affecting first the upper limbs and then the lower limbs. An albuminocytological dissociation was found in the cerebrospinal fluid study. Magnetic resonance imaging of the spinal cord showed enhancement and thickening of the cauda equina roots. The patient was treated with immunoglobulins with a favorable clinical outcome.
格林-巴利综合征/米勒-费舍尔综合征（GBS/MFS）重叠综合征是一种极为罕见的格林-巴利综合征（GBS）变异型，其中米勒-费舍尔综合征（MFS）与 GBS 的其他特征同时存在，如肢体无力、感觉异常和面瘫。我们报告了一例 12 岁无病理史患者的临床病例，其急性出现眼肌麻痹、反射消失、面瘫和吞咽及发音障碍，随后进行性、下行性和对称性无力影响上肢，然后影响下肢。脑脊液研究发现蛋白细胞分离。脊髓磁共振成像显示马尾神经根增强和增厚。该患者接受免疫球蛋白治疗，临床结果良好。
