Almaghrabi Reem S, Ali Batool, Al-Thawadi Sahar, Halim Magid Abdel, Alrajhi Abdulrahman A
Department of Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Ann Saudi Med. 2011 Jul-Aug;31(4):417-20. doi: 10.4103/0256-4947.76408.
Human immunodeficiency virus type 2 (HIV-2), the second retrovirus that causes the acquired immune deficiency syndrome (AIDS) in humans, is limited in its distribution to West Africa. We report cases in two Saudi families with HIV-2 infection and AIDS, resulting in death of the index cases-the husbands, while the wives and a daughter were maintained on antiretroviral therapy. When HIV viral loads were undetectable in initial assays, further testing confirmed the presence of HIV-2. In the first family, the 30-year-old wife was found to be HIV-positive after the diagnosis in her 30-year-old husband, who later died with AIDS. In the second family, HIV-2 infection was diagnosed in the 50-year-old wife and 18-year-old daughter of a man who had died of AIDS at the age of 48 years. Recognizing HIV-2 infection is essential for appropriate workup, assessment, therapy and care of the pregnant woman.
人类免疫缺陷病毒2型（HIV-2）是导致人类获得性免疫缺陷综合征（AIDS）的第二种逆转录病毒，其分布局限于西非。我们报告了两个沙特家庭中HIV-2感染和艾滋病的病例，导致首例病例（丈夫）死亡，而妻子和一个女儿接受抗逆转录病毒治疗。在最初检测中未检测到HIV病毒载量时，进一步检测证实存在HIV-2。在第一个家庭中，30岁的丈夫被诊断为艾滋病后死亡，其30岁的妻子随后被发现HIV呈阳性。在第二个家庭中，一名48岁死于艾滋病的男子的50岁妻子和18岁女儿被诊断为HIV-2感染。认识到HIV-2感染对于对孕妇进行适当的检查、评估、治疗和护理至关重要。
