Polonara Gabriele, Salvolini Simone, Fabri Mara, Mascioli Giulia, Cavola Gian Luca, Neri Piergiorgio, Mariotti Cesare, Giovannini Alfonso, Salvolini Ugo
Sezione Scienze Radiologiche, Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche, Università Politecnica delle Marche, Ancona, Italy,
Int Ophthalmol. 2011 Apr;31(2):129-34. doi: 10.1007/s10792-011-9420-5. Epub 2011 Feb 4.
To study the functional recovery of a patient with cerebrovascular injury using combined functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI). A 24-year-old woman with left hemianopsia underwent fMRI and DTI in a 1.5-tesla machine both in the acute phase and 1 month after an ischaemic stroke involving the right calcarine cortex. Acute-phase fMRI demonstrated that peripheral left visual field stimulation did not activate the right primary visual cortex, whereas stimulation 1 month later activated the visual cortex bilaterally. Analysis of acute-phase DTI data disclosed that a reduction of fractional anisotropy in the right optic radiation had almost resolved after 1 month. Fibre direction was normal at either time point. fMRI and DTI can demonstrate functional damage and recovery in patients with neuro-ophthalmological lesions.
采用功能磁共振成像（fMRI）和弥散张量成像（DTI）联合技术研究脑血管损伤患者的功能恢复情况。一名患有左侧偏盲的24岁女性在涉及右侧距状皮质的缺血性中风急性期及1个月后，于1.5特斯拉的机器上接受了fMRI和DTI检查。急性期fMRI显示，左侧周边视野刺激未激活右侧初级视觉皮层，而1个月后的刺激双侧激活了视觉皮层。急性期DTI数据分析显示，右侧视辐射各向异性分数降低在1个月后几乎完全恢复。两个时间点的纤维方向均正常。fMRI和DTI能够显示神经眼科病变患者的功能损害及恢复情况。
