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医学重症监护患者的医源性失血估算及贫血原因

Approximate iatrogenic blood loss in medical intensive care patients and the causes of anemia.

作者信息

Tosiri Pitima, Kanitsap Nonglak, Kanitsap Apichart

机构信息

Department ofMedicine, Faculty of Medicine, Thammasat University, Pathumthani, Thailand.

出版信息

J Med Assoc Thai. 2010 Dec;93 Suppl 7:S271-6.

PMID:21294425
Abstract

BACKGROUND

Anemia is the most common hematologic problem worldwide especially in developing world. There are many causes of anemia in ICU patient such as gastrointestinal bleeding, anemia of chronic inflammation, trauma or surgery. Patient who were admitted in the ICU need to have a lot of blood tests related to their illness and for further treatment, however that can cause decrease of hematocrit or anemia.

OBJECTIVE

To identify the estimate volume of blood drawn from medical ICU patients and find out whether the volume of blood drawn effects the Hemoglobin/Hematocrit (Hb/Hct) or anemia and to identify the cause of anemia in ICU patient.

MATERIAL AND METHOD

This is an observation prospective cohort study collecting the volume of blood drawn from patients who were admitted to ICU Thammasat university hospital during 1st October 2007 through 31st March 2008.

RESULTS

This study found the mean volume of blood samples drawn from ICU patients is 77.8 ml. Sixty-eight percents of patients had a decrease Hb/Hct level during admission and around sixteen percent had anemia during admission. There is no statistically significant between the volume of blood drawn and the decrease of Hb/Hct.

CONCLUSION

Decrease of Hb/Hct or anemia are common in ICU patient. This study showed that iatrogenic blood loss for laboratory investigation is one of the cause of anemia. We concluded that physician should order phlebotomy for necessary investigation for the most effective of diagnosis and treatment, but the less complication.

摘要

背景

贫血是全球最常见的血液学问题,尤其是在发展中国家。重症监护病房(ICU)患者贫血的原因有很多,如胃肠道出血、慢性炎症性贫血、创伤或手术。入住ICU的患者需要进行许多与疾病相关的血液检查以及进一步治疗,但这可能会导致血细胞比容降低或贫血。

目的

确定从医学ICU患者采集的估计血量,了解采血体积是否会影响血红蛋白/血细胞比容(Hb/Hct)或贫血情况,并确定ICU患者贫血的原因。

材料与方法

这是一项观察性前瞻性队列研究,收集了2007年10月1日至2008年3月31日期间入住泰国国立法政大学医院ICU患者的采血量。

结果

本研究发现,ICU患者采集的血样平均体积为77.8毫升。68%的患者在入院期间Hb/Hct水平下降,约16%的患者在入院期间患有贫血。采血体积与Hb/Hct下降之间无统计学显著差异。

结论

Hb/Hct降低或贫血在ICU患者中很常见。本研究表明,因实验室检查导致的医源性失血是贫血的原因之一。我们得出结论,医生应进行必要的放血检查以实现最有效的诊断和治疗,但并发症要少。

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