Li Michelle Pui-Ming, Jelinek George A, Weiland Tracey J, Mackinlay Claire A, Dye Sherelle, Gawler Ian
Emergency Practice Innovation Centre, St Vincent's Hospital and Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Australia.
Qual Prim Care. 2010;18(6):379-89.
To evaluate the effect of a residential retreat on promoting lifestyle modification for the health-related quality of life (HRQOL) of people with multiple sclerosis (MS).
A longitudinal cohort study of adults with self-reported MS who voluntarily attended a five-day residential retreat in rural Victoria, Australia. Participants were asked to complete the MSQOL-54 questionnaire just prior to the retreat, and at one year and 2.5 years post-retreat.
Of 188 participants 109 (58%) completed the questionnaire. The cohort showed a significant improvement in HRQOL at one year and 2.5 year follow-up. After one year, overall quality of life (QOL) domain had increased from 73.4 to 81.7 (P<0.001), physical health composite from 66.2 to 76.4 (P=0.001) and mental health composite from 73.7 to 83.6 (P<0.001) in the subset of 76 with data at both time points. After 2.5 years, overall QOL had increased from 68.4 to 71.7 (P=0.03), physical health 59.7 to 70.0 (P=0.01), and mental health 66.9 to 76.6 (P<0.01) in the subset of 44 with data at both time points.
HRQOL usually deteriorates over time in people with MS. Attendance at a residential retreat promoting lifestyle modification appears to have a significant short-medium term positive effect on QOL for people with MS. General practitioners caring for people with MS should consider the potential benefits of this approach in overall management.
评估一次住宿疗养对促进多发性硬化症（MS）患者改善生活方式以提高健康相关生活质量（HRQOL）的效果。
对自我报告患有MS的成年人进行一项纵向队列研究，这些成年人自愿参加了在澳大利亚维多利亚州农村地区举行为期五天的住宿疗养。要求参与者在疗养前、疗养后一年和2.5年时完成MSQOL - 54问卷。
188名参与者中，109名（58%）完成了问卷。该队列在一年和2.5年随访时HRQOL有显著改善。一年后，在两个时间点均有数据的76名参与者子集中，总体生活质量（QOL）领域从73.4提高到81.7（P<0.001），身体健康综合评分从66.2提高到76.4（P = 0.001），心理健康综合评分从73.7提高到83.6（P<0.001）。2.5年后，在两个时间点均有数据的44名参与者子集中，总体QOL从68.4提高到71.7（P = 0.03），身体健康从59.7提高到70.0（P = 0.01），心理健康从66.9提高到76.6（P<0.01）。
MS患者的HRQOL通常会随着时间推移而恶化。参加促进生活方式改变的住宿疗养似乎对MS患者的QOL有显著的中短期积极影响。照顾MS患者的全科医生应在整体管理中考虑这种方法的潜在益处。
