[腭心面综合征的头影测量研究：畸形对发声的影响]

[Cephalometric study of the velocardiofacial syndrome: Impact of dysmorphosis on phonation].

作者信息

Leveau-Geffroy S, Perrin J-P, Khonsari R H, Mercier J

机构信息

Service de Chirurgie Maxillo-Faciale et Stomatologie, CHRU, 1, Place Alexis-Ricordeau, 44093 Nantes, France.

出版信息

Rev Stomatol Chir Maxillofac. 2011 Feb;112(1):11-5. doi: 10.1016/j.stomax.2011.01.002. Epub 2011 Feb 3.

DOI:10.1016/j.stomax.2011.01.002

PMID:21295320

Abstract

INTRODUCTION

Velopharyngeal insufficiency is a frequent sign of the velocardiofacial syndrome (VCFS) but its origins are not well-documented. Our aim was to establish a correlation between this functional disorder and regional morphological anomalies.

PATIENTS AND METHODS

Twenty-seven of 36 patients presenting with VCFS could be included retrospectively. We measured cavum depth and velum length on lateral orthodontic X-rays, and assessed the relationship between these two measures. We compared these measures to those of reference populations. Postoperative phonation was assessed with an aerophonoscope.

RESULTS

The patients presented with a short velum and a deep cavum. Cranium base and upper cervical spine were malformed in 22 of the 27 patients. Seventeen of the 23 assessed patients (66%) improved their phonation after surgery.

DISCUSSION

Our data suggests that velopharyngeal insufficiency in VCFS could be the result of a more global craniospinal growth disorder the functional consequences of which remain unclear. The frequent association of morphological anomalies with mental retardation is probably responsible for the failure to normalize phonation.

摘要