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心脏血管瘤。十例临床病理研究。

Hemangiomas of the heart. A clinicopathologic study of ten cases.

作者信息

Burke A, Johns J P, Virmani R

机构信息

Department of Cardiovascular Pathology, Armed Forces Institute of Pathology, Washington, D.C.

出版信息

Am J Cardiovasc Pathol. 1990;3(4):283-90.

PMID:2129569
Abstract

The clinical and histopathologic features of 10 cardiac hemangiomas are presented. The patients' ages ranged from 2 weeks to 65 years (mean: 32 years). Eight patients had no other cardiovascular abnormalities, one was associated with intra-atrial lipoma, and one was associated with an anomalous origin of the left coronary artery. One patient had other hemangiomas of the oral cavity and small intestine. The tumors presented as pericardial effusion (2), sudden death (2), shortness of breath (1), incidental finding on chest X-ray (1), asymptomatic murmur (1), syncope (1), and incidental finding at autopsy (2). Location of the tumors included the right ventricle (4), left ventricle (3), atrial septum (2), and right atrium (1). All six tumors presenting in life were resected successfully, one requiring placement of a synthetic graft. Cardiac hemangiomas are usually sporadic; presenting symptoms depend on location in the heart; arrhythmias or sudden death can occur if the tumor is present in the basal region of the ventricular septum; surgical resection is feasible in other locations.

摘要

本文介绍了10例心脏血管瘤的临床和组织病理学特征。患者年龄从2周龄至65岁不等(平均32岁)。8例患者无其他心血管异常,1例合并心房脂肪瘤,1例合并左冠状动脉异常起源。1例患者同时患有口腔和小肠的其他血管瘤。肿瘤表现为心包积液(2例)、猝死(2例)、呼吸急促(1例)、胸部X线检查偶然发现(1例)、无症状杂音(1例)、晕厥(1例)以及尸检偶然发现(2例)。肿瘤位置包括右心室(4例)、左心室(3例)、房间隔(2例)和右心房(1例)。所有6例生前出现症状的肿瘤均成功切除,1例需要植入人工血管。心脏血管瘤通常为散发性;出现的症状取决于肿瘤在心脏中的位置;如果肿瘤位于室间隔基部区域,可发生心律失常或猝死;在其他位置可行手术切除。

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