Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway, Atlanta, GA 30341, USA.
Inj Prev. 2011 Oct;17(5):332-7. doi: 10.1136/ip.2010.029793. Epub 2011 Feb 4.
To describe poisoning hospitalisations among reproductive-aged women from 1998 to 2006.
1998-2006 data from the Nationwide Inpatient Sample of the Healthcare Cost and Utilisation Project were used to identify hospitalisations for poisonings among US women aged 15-44 years. Differences in hospitalisation characteristics were compared by intent using χ(2) statistics. Trends in poisoning hospitalisation rates were calculated overall and by subgroup.
There were approximately 636,000 poisoning hospitalisations in women aged 15-44 years during 1998-2006. Hospitalisations for intentionally self-inflicted poisonings had a higher proportion of women aged 15-24 years and privately insured women than did unintentional poisonings (p<0.001). Poisoning hospitalisations in rural areas and those that resulted in death were more likely to be of undetermined intent than those for which intent was specified (p<0.001). Co-diagnoses of substance abuse (34.5%) or mental disorders (66.5%) were high. The rate of poisoning hospitalisations overall and unintentional poisoning hospitalisations increased 6% and 22%, respectively, during this period (p<0.001). The most frequently diagnosed poisoning agent was acetaminophen. Poisonings attributable to acetaminophen, opioids, central nervous system stimulants and benzodiazepines increased, while poisonings attributable to antidepressants decreased (p<0.05).
The increase in unintentional poisoning hospitalisations among women aged 15-44 years and the changing profile of poisoning agents should inform the healthcare community's poisoning prevention strategies. Poisoning prevention strategies should include a component to address substance abuse and mental health disorders among reproductive-age women.
描述 1998 年至 2006 年期间生育年龄妇女的中毒住院情况。
使用 1998 年至 2006 年期间医疗保健成本和利用项目的全国住院患者样本中的数据,确定美国 15-44 岁女性的中毒住院病例。使用卡方检验比较不同意图的住院特征差异。计算总体和亚组的中毒住院率趋势。
在 1998 年至 2006 年期间,15-44 岁女性中毒住院人数约为 63.6 万例。与非故意中毒相比,故意自我中毒的住院病例中 15-24 岁和私人保险的女性比例更高(p<0.001)。农村地区和导致死亡的中毒住院更可能是无法确定意图的,而不是有明确意图的(p<0.001)。合并物质滥用(34.5%)或精神障碍(66.5%)的诊断率较高。在此期间,总体中毒住院率和非故意中毒住院率分别增加了 6%和 22%(p<0.001)。最常见的中毒药物是对乙酰氨基酚。与对乙酰氨基酚、阿片类药物、中枢神经系统兴奋剂和苯二氮䓬类药物相关的中毒有所增加,而与抗抑郁药相关的中毒有所减少(p<0.05)。
15-44 岁女性非故意中毒住院率的增加以及中毒药物种类的变化,应引起医疗保健界对中毒预防策略的重视。中毒预防策略应包括解决生育年龄妇女物质滥用和精神健康障碍的内容。