Diao Zongli, Wang Jing, Qi Haiyu, Li Xiaoli, Zheng Xiaoyan, Yin Chenghong
Beijing Tropical Medicine Research Institute, Beijing Friendship Hospital, Capital Medical University, 95 Yong-An Road, Beijing 100050, China.
Trop Doct. 2011 Apr;41(2):76-8. doi: 10.1258/td.2010.100294. Epub 2011 Feb 4.
Human ocular angiostrongyliasis caused by Angiostrongylus cantonensis infection in the eye is a very rare condition. Until now, there has been no comprehensive analysis of this disease. We searched and analysed the references found on the Internet that refer to human ocular angiostrongyliasis and reviewed the aetiology, clinical manifestations, diagnosis, epidemiology and treatment of the condition. Twenty-six references were found reporting 35 patients from 10 countries that were diagnosed with human ocular angiostrongyliasis. People are usually infected by eating raw or undercooked intermediate hosts of the parasite such as snails or contaminated vegetables. The most common symptom was visual loss. Although several treatments have been used, ocular angiostrongyliasis can still result in permanent visual impairment and may even cause blindness. As the eye is the site of infection and direct visualization is possible, ocular examination is crucial for diagnosis. The therapeutic success depended on early and complete surgical removal.
由广州管圆线虫感染眼部引起的人类眼部管圆线虫病是一种非常罕见的病症。到目前为止，尚未对这种疾病进行全面分析。我们搜索并分析了在互联网上找到的提及人类眼部管圆线虫病的参考文献，并回顾了该病的病因、临床表现、诊断、流行病学和治疗方法。发现26篇参考文献报道了来自10个国家的35例被诊断为人类眼部管圆线虫病的患者。人们通常因食用寄生虫的生的或未煮熟的中间宿主（如蜗牛）或受污染的蔬菜而感染。最常见的症状是视力丧失。尽管已经采用了几种治疗方法，但眼部管圆线虫病仍可导致永久性视力损害，甚至可能导致失明。由于眼睛是感染部位且可以直接观察，眼部检查对诊断至关重要。治疗成功取决于早期和彻底的手术切除。
