结核分枝杆菌可以利用血红素作为铁源。
Mycobacterium tuberculosis can utilize heme as an iron source.
机构信息
Department of Microbiology, University of Alabama at Birmingham, 609 Bevill Biomedical Research Building, 845 19th Street South, Birmingham, AL 35294, USA.
出版信息
J Bacteriol. 2011 Apr;193(7):1767-70. doi: 10.1128/JB.01312-10. Epub 2011 Feb 4.
Abstract
Most iron in mammals is found within the heme prosthetic group. Consequently, many bacterial pathogens possess heme acquisition systems to utilize iron from the host. Here, we demonstrate that Mycobacterium tuberculosis can utilize heme as an iron source, suggesting that M. tuberculosis possesses a yet-unknown heme acquisition system.
摘要
哺乳动物体内的大部分铁存在于血红素辅基中。因此，许多细菌病原体拥有从宿主中获取铁的血红素获取系统。在这里，我们证明结核分枝杆菌可以利用血红素来作为铁源，这表明结核分枝杆菌拥有一个未知的血红素获取系统。
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