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本文引用的文献

1
Comparative genome biology of a serogroup B carriage and disease strain supports a polygenic nature of meningococcal virulence.B 群带菌和疾病菌株的比较基因组生物学支持脑膜炎球菌毒力的多基因性质。
J Bacteriol. 2010 Oct;192(20):5363-77. doi: 10.1128/JB.00883-10. Epub 2010 Aug 13.
2
The meningococcal vaccine candidate neisserial surface protein A (NspA) binds to factor H and enhances meningococcal resistance to complement.脑膜炎奈瑟菌候选疫苗表面蛋白 A（NspA）与因子 H 结合，增强脑膜炎奈瑟菌对补体的抵抗力。
PLoS Pathog. 2010 Jul 29;6(7):e1001027. doi: 10.1371/journal.ppat.1001027.
3
NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitidis.NeMeSys：缩小人类病原体脑膜炎奈瑟菌序列和功能之间差距的生物资源。
Genome Biol. 2009;10(10):R110. doi: 10.1186/gb-2009-10-10-r110. Epub 2009 Oct 9.
4
Genome flexibility in Neisseria meningitidis.脑膜炎奈瑟菌的基因组灵活性
Vaccine. 2009 Jun 24;27 Suppl 2(Suppl 2):B103-11. doi: 10.1016/j.vaccine.2009.04.064. Epub 2009 May 27.
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Global epidemiology of meningococcal disease.脑膜炎球菌病的全球流行病学
Vaccine. 2009 Jun 24;27 Suppl 2:B51-63. doi: 10.1016/j.vaccine.2009.04.063. Epub 2009 May 27.
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Aggressive assembly of pyrosequencing reads with mates.将焦磷酸测序读数与配对序列进行积极组装。
Bioinformatics. 2008 Dec 15;24(24):2818-24. doi: 10.1093/bioinformatics/btn548. Epub 2008 Oct 24.
7
Infectious disease. An ill wind, bringing meningitis.传染病。一阵恶风，带来脑膜炎。
Science. 2008 Jun 27;320(5884):1710-5. doi: 10.1126/science.320.5884.1710.
8
Whole-genome comparison of disease and carriage strains provides insights into virulence evolution in Neisseria meningitidis.疾病菌株与携带菌株的全基因组比较为脑膜炎奈瑟菌的毒力进化提供了见解。
Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3473-8. doi: 10.1073/pnas.0800151105. Epub 2008 Feb 27.
9
Characterization of ST-4821 complex, a unique Neisseria meningitidis clone.ST-4821复合体的特性分析，一种独特的脑膜炎奈瑟菌克隆。
Genomics. 2008 Jan;91(1):78-87. doi: 10.1016/j.ygeno.2007.10.004. Epub 2007 Nov 26.
10
Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18.通过对C群菌株FAM18的比较分析观察脑膜炎球菌的遗传变异机制。
PLoS Genet. 2007 Feb 16;3(2):e23. doi: 10.1371/journal.pgen.0030023. Epub 2006 Dec 21.

转化奈瑟氏脑膜炎球菌 A 群菌株 WUE2594 的全基因组序列。

Whole-genome sequence of the transformable Neisseria meningitidis serogroup A strain WUE2594.

机构信息

Institute for Hygiene and Microbiology, University of Würzburg, Würzburg, Germany.

出版信息

J Bacteriol. 2011 Apr;193(8):2064-5. doi: 10.1128/JB.00084-11. Epub 2011 Feb 4.

DOI:10.1128/JB.00084-11
PMID:21296965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3133043/
Abstract

Serogroup A meningococci are a leading cause of bacterial meningitis in children and young adults worldwide. However, the genetic basis of serogroup A strains' virulence and their epidemiological properties remain poorly understood. Therefore, we sequenced the complete genome of the transformable Neisseria meningitidis serogroup A strain WUE2594.

摘要

A 群脑膜炎奈瑟球菌是全世界导致儿童和青年细菌性脑膜炎的主要病因。然而，A 群菌株毒力的遗传基础及其流行病学特性仍知之甚少。因此，我们对可转化的脑膜炎奈瑟球菌 A 群血清型菌株 WUE2594 进行了全基因组测序。