Kumar Praveen, Gupta Ak, Sood Shashank, Verma Ashok Kumar
Department of Radiodiagnosis, GSVM Medical College, Kanpur, India.
Surg Neurol Int. 2011 Jan 24;2:11. doi: 10.4103/2152-7806.76148.
Spinal cord compression in flourosis is a common complication. These complications are mainly due to compression of the spinal cord by thickening and ossification of posterior longitudinal ligament and ligamentum flavum. Surgical decompression is the treatment of choice for fluorotic spinal cord compression. The recurrence of spinal cord compression after surgical decompression in flourosis is a rare event.
We are presenting a case of a 63-year-old man who belonged to Kanpur, an endemic fluorosis region in India, with symptoms of cervical cord compression cranial to the operative site, 20 years after laminectomy for cervical fluorotic myelopathy. Urinary and serum fluoride levels were elevated. The patient underwent a skeletal survey: computed tomography and magnetic resonance imaging of the cervical spine showed a postoperative defect of laminectomy, osteosclerosis, osteophyte formation, calcification of the intraosseus membrane in the forearm, thickening and ossification of the posterior longitudinal ligament at C1, thickening and ossification of the residual ligamentum flavum at C1/C2, and dural calcification at the C2 vertebral level and compressive myelopathy. The patient refused surgical decompression and was managed with tizanidine HCl (an antispasticity medicine), a sublingual single night dose, 8 mg for symptomatic relief.
The recurrence of spinal cord compression in the fluorotic spine 20 years after laminectomy is a very unusual event and hence the patient should be kept under observation for a long duration. This case report contributes to the literature associated with the management of fluorotic spine.
氟骨症中的脊髓压迫是一种常见并发症。这些并发症主要是由于后纵韧带和黄韧带增厚及骨化对脊髓的压迫所致。手术减压是氟骨症性脊髓压迫的首选治疗方法。氟骨症手术减压后脊髓压迫复发是罕见事件。
我们报告一例63岁男性,来自印度地方性氟骨症流行区坎普尔,在因颈椎氟骨症性脊髓病行椎板切除术后20年,出现手术部位上方颈髓压迫症状。尿氟和血清氟水平升高。患者接受了骨骼检查:颈椎计算机断层扫描和磁共振成像显示椎板切除术后缺损、骨质硬化、骨赘形成、前臂骨内韧带钙化、C1水平后纵韧带增厚及骨化、C1/C2水平残余黄韧带增厚及骨化、C2椎体水平硬脊膜钙化以及压迫性脊髓病。患者拒绝手术减压,采用盐酸替扎尼定(一种抗痉挛药物)进行治疗,舌下含服单晚剂量8mg以缓解症状。
椎板切除术后20年氟骨症性脊柱脊髓压迫复发是非常罕见的事件,因此应长期对患者进行观察。本病例报告为氟骨症性脊柱治疗的相关文献提供了资料。