Lammers A J J
Uit de afdeling ITA/Interne Geneeskunde van het Academisch Medisch Centrum in Amsterdam/Universitieit van Amsterdam.
Ned Tijdschr Tandheelkd. 2010 Dec;117(12):611-4. doi: 10.5177/ntvt.2010.12.10195.
The spleen plays a significant role in the defence against infections, especially infections caused by encapsulated bacteria, such as Streptococcus pneumoniae. In case of (functional) asplenia, a fulminant sepsis with a high mortality rate may develop in a short time. Preventive measures are therefore recommended for people without a spleen or who have a dysfunctional spleen. A dysfunctional spleen may be present in diseases such as sickle cell anaemia, ulcerative colitis, Crohn's disease and coeliac disease. Preventive measures consist of vaccinations, antibiotics and patient education. Unfortunately, however, it has been shown that these preventive measures are not adequately followed. Currently, a Dutch guideline for healthcare providers is being developed.
脾脏在抵御感染方面发挥着重要作用，尤其是针对由包膜细菌引起的感染，如肺炎链球菌。在（功能性）无脾的情况下，可能会在短时间内发生死亡率很高的暴发性败血症。因此，建议对无脾或脾脏功能不全的人采取预防措施。脾脏功能不全可能存在于镰状细胞贫血、溃疡性结肠炎、克罗恩病和乳糜泻等疾病中。预防措施包括接种疫苗、使用抗生素以及对患者进行教育。然而，遗憾的是，已表明这些预防措施未得到充分落实。目前，荷兰正在为医疗服务提供者制定一项指南。
