Tamire Abebe Habtamu, Million Tenagne
Department of Pediatrics and Child Health, Addis Ababa University, College of Health Sciences, Addis Ababa, Ethiopia.
Out Patient Department, Meron Medium Clinic, Addis Ababa, Ethiopia.
Int Med Case Rep J. 2024 May 21;17:521-525. doi: 10.2147/IMCRJ.S453861. eCollection 2024.
Sickle cell disease (SCD) is a hereditary blood disorder characterized by abnormal hemoglobin, resulting in various clinical manifestations. Recognizing the complex clinical picture of SCD is crucial for physicians to effectively diagnose and manage the disease. While typical presentations may be absent, it is important to consider the possibility of SCD in patients presenting with ulcerative colitis (UC). The concurrent occurrence of UC and SCD is extremely rare. Therefore, a comprehensive investigation is warranted for individuals at risk of developing SCD with UC. In this report, we presented the first documented case of a child in Ethiopia with both SCD and UC.
镰状细胞病（SCD）是一种遗传性血液疾病，其特征是血红蛋白异常，导致各种临床表现。认识到SCD复杂的临床症状对于医生有效诊断和管理该疾病至关重要。虽然可能没有典型表现，但对于患有溃疡性结肠炎（UC）的患者，考虑SCD的可能性很重要。UC和SCD同时发生极为罕见。因此，对于有患SCD合并UC风险的个体，有必要进行全面调查。在本报告中，我们介绍了埃塞俄比亚首例有记录的同时患有SCD和UC的儿童病例。
