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口服碘酊后发生急性溶血。

Acute hemolysis following iodine tincture ingestion.

机构信息

Division of Clinical Toxicology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.

出版信息

Hum Exp Toxicol. 2011 Oct;30(10):1716-9. doi: 10.1177/0960327111398677. Epub 2011 Feb 7.

DOI:10.1177/0960327111398677
PMID:21300686
Abstract

Iodine tincture poisoning is uncommon regardless of its widespread use as an antiseptic in daily practice. Previously reported effects of iodine-containing antiseptic poisoning included topical irritation, corrosive effects, allergic response, and hepatic or renal injury, which mainly resulted from complications of topical use during surgical procedures. We herein reported an unusual case of severe hemolysis and acute renal failure following intentional ingestion of iodine tincture containing 60 mg/ml iodine and 40 mg/ml potassium iodide in 70% v/v ethanol. The patient completely recovered 8 weeks later after receiving supportive treatment, plasma exchange, and temporary hemodialysis.

摘要

尽管碘酊作为一种日常实践中的消毒剂被广泛使用,但碘酊中毒并不常见。以前报道的含碘消毒剂中毒的影响包括局部刺激、腐蚀性作用、过敏反应和肝或肾损伤,这些主要是由于手术过程中局部使用的并发症引起的。我们在此报告了一例罕见的病例,患者故意摄入含 60mg/ml 碘和 40mg/ml 碘化钾的 70%乙醇中的碘酊,导致严重溶血和急性肾衰竭。患者在接受支持治疗、血浆置换和临时血液透析后 8 周完全康复。

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Hum Exp Toxicol. 2011 Oct;30(10):1716-9. doi: 10.1177/0960327111398677. Epub 2011 Feb 7.
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