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位于拉布岛的本笃会修道院隐藏着阳光对黄斑变性(AMD)发展影响的奥秘。阳光是有害的、黄斑变性的风险因素还是病因呢?

Benedictine monastery on the Island of Rab hides the mystery of sunlight influence on development of macular degeneration (AMD). Is a harmful sunlight, risk factor or cause of macular degeneration?

作者信息

Vojniković Bozo, Vojniković Davor

机构信息

Daily Eye Clinic Dr. Bozo Vojniković, Rijeka, Croatia.

出版信息

Coll Antropol. 2010 Apr;34 Suppl 2:5-8.

Abstract

Benedictine Monastery of St. Andrew is probably the oldest existing Benedictine monastery in this area. According to hundreds of years of legend, it was founded in 1018 year. In clinical examination about the possibility of the macular degeneration occurrence in 15 Benedictine sisters, we found the age-related macular degeneration (AMD) in two cases only. In 13 other sisters aging 27, 60, 67years, the fundus picture was like in a baby, vision, visual field and meridian thresholds were normal. What is the explanation for this phenomenon? Two sisters with AMD work and live as the farm workers, but the other sisters live in closed monastery with very low natural sunlight, approximately 300-500 lx. In conclusion, the earlier author's experimental and clinical works follow the consequence that without exposure of eyes to harmful higher doses of sunlight, it is not possible to develop AMD. The harmful cumulative dose of sunlight is not the risk factor but the cause, including the inheritance, for AMD development.

摘要

圣安德鲁本笃会修道院可能是该地区现存最古老的本笃会修道院。根据数百年的传说,它建于1018年。在对15名本笃会修女发生黄斑变性可能性的临床检查中,我们仅在两例中发现了年龄相关性黄斑变性(AMD)。在其他13名年龄分别为27岁、60岁、67岁的修女中,眼底图像如同婴儿,视力、视野和子午线阈值均正常。如何解释这一现象?两名患有AMD的修女从事农活并生活在户外,而其他修女生活在封闭的修道院内,自然阳光非常少,约为300 - 500勒克斯。总之,早期作者的实验和临床研究结果表明,如果眼睛不暴露于有害的高剂量阳光下,就不可能发生AMD。阳光的有害累积剂量不是AMD发生的风险因素,而是包括遗传因素在内的AMD发生的原因。

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