Dipartimento di Fisica e Tecnologie Relative, Università di Palermo, Viale delle Scienze, Edificio 18, Palermo 90128, Italy.
Med Phys. 2010 Dec;37(12):6147-56. doi: 10.1118/1.3512804.
Direct measurement of mammographic x-ray spectra under clinical conditions is a difficult task due to the high fluence rate of the x-ray beams as well as the limits in the development of high resolution detection systems in a high counting rate environment. In this work we present a detection system, based on a CdTe detector and an innovative digital pulse processing (DPP) system, for high-rate x-ray spectroscopy in mammography.
The DPP system performs a digital pile-up inspection and a digital pulse height analysis of the detector signals, digitized through a 14-bit, 100 MHz digitizer, for x-ray spectroscopy even at high photon counting rates. We investigated on the response of the digital detection system both at low (150 cps) and at high photon counting rates (up to 500 kcps) by using monoenergetic x-ray sources and a nonclinical molybdenum anode x-ray tube. Clinical molybdenum x-ray spectrum measurements were also performed by using a pinhole collimator and a custom alignment device.
The detection system shows excellent performance up to 512 kcps with an energy resolution of 4.08% FWHM at 22.1 keV. Despite the high photon counting rate (up to 453 kcps), the molybdenum x-ray spectra, measured under clinical conditions, are characterized by a low number of pile-up events. The agreement between the attenuation curves and the half value layer values, obtained from the measured spectra, simulated spectra, and from the exposure values directly measured with an ionization chamber, also shows the accuracy of the measurements.
These results make the proposed detection system a very attractive tool for both laboratory research and advanced quality controls in mammography.
由于射线束的高通量率以及在高计数率环境中开发高分辨率检测系统的限制,在临床条件下直接测量乳腺 X 射线光谱是一项艰巨的任务。在这项工作中,我们提出了一种基于 CdTe 探测器和创新的数字脉冲处理(DPP)系统的检测系统,用于乳腺 X 射线光谱学中的高速率 X 射线光谱学。
DPP 系统对探测器信号进行数字堆积检查和数字脉冲高度分析,通过 14 位、100MHz 的数字化仪进行数字化,即使在高光子计数率下也可以进行 X 射线光谱学。我们通过使用单能 X 射线源和非临床钼阳极 X 射线管研究了数字检测系统在低(150cps)和高光子计数率(高达 500kcps)下的响应。还使用针孔准直器和定制对准装置进行了临床钼 X 射线光谱测量。
该检测系统在高达 512kcps 的计数率下表现出优异的性能,在 22.1keV 时的能量分辨率为 4.08%FWHM。尽管光子计数率很高(高达 453kcps),但在临床条件下测量的钼 X 射线光谱的堆积事件数量却很低。从测量的光谱、模拟的光谱以及通过电离室直接测量的曝光值得出的衰减曲线和半值层值之间的一致性也表明了测量的准确性。
这些结果使所提出的检测系统成为实验室研究和乳腺摄影高级质量控制的非常有吸引力的工具。