School of Pharmacy, Kitasato University, Tokyo, Japan.
Org Lett. 2011 Mar 4;13(5):1158-61. doi: 10.1021/ol200022a. Epub 2011 Feb 9.
The first total synthesis of citridone A has been achieved through regioselective intramolecular iodocyclization and regio- and stereoselective Pd(0)-catalyzed coupling as key reactions.
通过区域选择性的分子内碘化环化和区域和立体选择性的 Pd(0)催化偶联反应,首次实现了 citridone A 的全合成。