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牛磺酸补充剂对囊性纤维化患者生长、脂肪吸收及胆汁酸的影响。

Effect of taurine supplements on growth, fat absorption and bile acid on cystic fibrosis.

作者信息

Carrasco S, Codoceo R, Prieto G, Lama R, Polanco I

机构信息

Department of Pediatrics, Children's Hospital La Paz, Autonoma University, Madrid, Spain.

出版信息

Acta Univ Carol Med (Praha). 1990;36(1-4):152-6.

PMID:2130680
Abstract

We have evaluated the effect of taurine supplementation nutritional status, steatorrhea and bile acid in twenty two Cystic Fibrosis patients. Weight increased in fifty per cent and height in forty eight per cent of them. Steatorrhea improved significantly in six patients of group II. Glycine/taurine ratio was reduced. Bile acid malabsorption improved only in the patients with high degree of steatorrhea. Serum bile acid was observed significantly elevated in both groups. This results suggest that taurine supplementation can be useful adjunct from of therapy in Cystic Fibrosis patients with fat malabsorption.

摘要

我们评估了补充牛磺酸对22例囊性纤维化患者营养状况、脂肪泻和胆汁酸的影响。其中50%的患者体重增加,48%的患者身高增加。第二组中有6例患者的脂肪泻明显改善。甘氨酸/牛磺酸比值降低降低降低。仅在脂肪泻程度较高的患者中胆汁酸吸收不良有所改善。两组患者的血清胆汁酸均显著升高。这些结果表明,补充牛磺酸可能是治疗脂肪吸收不良的囊性纤维化患者的一种有用辅助疗法。

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