Primary Care Research Unit of Bizkaia, Basque Healthcare Service-Osakidetza, Luis Power, 18-4(a) Planta, 48014 Bilbao, Spain.
Eur Psychiatry. 2011 Oct;26(7):428-35. doi: 10.1016/j.eurpsy.2010.11.002. Epub 2011 Feb 8.
To describe and compare the prevalence of mental disorders across primary care populations, and estimate their impact on quality of life.
Cross-sectional multilevel analysis of a systematic sample of 2539 attendees to eight primary care centres in different regions of Spain, assessed with the WHO Composite International Diagnostic Interview (CIDI 1.1), the Short Form Health Survey (SF-36) quality of life questionnaire and the SF-6D utility index.
The 12-month prevalence of any mental disorder was 23% (95% confidence interval: 21-24%), 10% had mood, 9% anxiety, 5% organic, 4% somatoform, and 1% alcohol use disorders, with a significant between-centre variability (P<0.001). People with mental disorders had one standard deviation lower mental quality of life than the general population. We estimated that 1831 quality-adjusted life-years (QALYs) are lost annually per 100,000 patients due to mental disorders, without considering mortality. Mood disorders have the worst impact with an annual loss of 1124 QALYs per 100,000 patients, excluding mortality (95% confidence interval: 912-1351).
Prevalence rates were similar to those obtained in international studies using the same diagnostic instrument and, given the significant between-centre variability found, it is recommended that mental health statistics be considered at small area level. Mental disorders, and especially mood disorders, are associated with very poor quality of life and higher scores on disability indexes than other common chronic conditions.
描述和比较初级保健人群中心理障碍的患病率,并评估其对生活质量的影响。
对西班牙 8 个不同地区的 2539 名初级保健中心就诊者进行了系统抽样,采用世界卫生组织复合国际诊断访谈(CIDI 1.1)、简明健康调查问卷(SF-36)生活质量问卷和 SF-6D 效用指数进行横断面多水平分析。
任何精神障碍的 12 个月患病率为 23%(95%置信区间:21-24%),10%有心境障碍,9%有焦虑症,5%有器质性障碍,4%有躯体形式障碍,1%有酒精使用障碍,各中心间存在显著差异(P<0.001)。患有精神障碍的人比一般人群的心理健康质量低一个标准差。我们估计,每年每 10 万患者因精神障碍而损失 1831 个质量调整生命年(QALY),不考虑死亡率。心境障碍的影响最严重,每年每 10 万患者损失 1124 个 QALY,不包括死亡率(95%置信区间:912-1351)。
患病率与使用相同诊断工具的国际研究结果相似,鉴于发现的中心间显著差异,建议在小区域水平考虑心理健康统计数据。精神障碍,特别是心境障碍,与非常差的生活质量和比其他常见慢性疾病更高的残疾指数得分相关。