Bettinelli M E, Civardi A, Costantini D, Padoan R, Giunta A, Cesana B, Greco L, Salvatore D, Santamaria F, Castro M
Dept. of Pediatrics, University of Milan, Italy.
Acta Univ Carol Med (Praha). 1990;36(1-4):215-6.
An Italian multicenter study has been carried out in order to obtain data on survival and prognostic factors in CF. We report data from four CF Centers: Milan, Neaples, Cagliari, Rome, Anagraphic data, mode of presentation and of diagnosis were collected, using CFDB database, from 536 CF pts. 39 pts had meconium ileus (7.3%); 269 (50%) were diagnosed before 12 months of age. 27 pts were lost to follow-up (5%); and 65 pts died (12%). Statistical analysis was performed by Kaplan-Meier survival curves compared by Logrank test.
为了获取囊性纤维化（CF）患者生存情况及预后因素的数据，开展了一项意大利多中心研究。我们报告了来自四个CF中心的数据：米兰、那不勒斯、卡利亚里、罗马。利用CFDB数据库，收集了536例CF患者的病历数据、临床表现及诊断方式。39例患者有胎粪性肠梗阻（7.3%）；269例（50%）在12个月龄前被诊断。27例患者失访（5%）；65例患者死亡（12%）。采用Kaplan-Meier生存曲线进行统计分析，并通过对数秩检验进行比较。
