Department of Surgery, University of Toronto, and the Li Ka Shing Knowledge Institute, St. Michael's Hospital, 4th Floor Bond Wing, Room 4-007, 30 Bond Street, Toronto, Ontario, M5B 1W8, Canada,
Curr Infect Dis Rep. 2010 Sep;12(5):345-53. doi: 10.1007/s11908-010-0126-z.
Source control refers to the spectrum of physical measures that are undertaken to control a focus of infection, and to facilitate restoration of optimal anatomy and physiology. These measures are classified as drainage-the evacuation of infected liquid through the creation of a controlled sinus or fistula, debridement-the physical removal of necrotic infected tissue, device removal, and the definitive measures that comprise the process of reconstruction and rehabilitation. Effective and timely source control is critical to the successful management of life-threatening infection. This article reviews the principles of diagnosis and source-control management, and their application to common infections that result in severe sepsis and septic shock.
源头控制是指采取物理措施来控制感染灶，并促进最佳解剖和生理功能恢复的一系列措施。这些措施可分为引流（通过创建可控窦道或瘘管排出受感染的液体）、清创术（清除坏死的受感染组织）、去除器械以及重建和康复过程中包含的明确措施。有效的及时源头控制对于成功治疗危及生命的感染至关重要。本文回顾了诊断和源头控制管理的原则及其在导致严重脓毒症和感染性休克的常见感染中的应用。
