Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China; Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, China.
Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China; Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, China.
Chin J Traumatol. 2020 Dec;23(6):311-313. doi: 10.1016/j.cjtee.2020.07.003. Epub 2020 Aug 3.
Intra-abdominal infection (IAI) is a deadly condition in which the outcome is associated with urgent diagnosis, assessment and management, including fluid resuscitation, antibiotic administration while obtaining further laboratory results, attaining precise measurements of hemodynamic status, and pursuing source control. This last item makes abdominal sepsis a unique treatment challenge. Delayed or inadequate source control is an independent predictor of poor outcomes and recognizing source control failure is often difficult or impossible. Further complicating issue in the debate is surrounding the timing, adequacy, and procedures of source control. This review evaluated and summarized the current approach and challenges in IAI management, which are the future research directions.
腹腔感染（IAI）是一种致命的病症，其预后与紧急诊断、评估和管理相关，包括液体复苏、在获得进一步实验室结果的同时给予抗生素治疗、准确测量血流动力学状态，并进行源头控制。最后这一点使得腹腔脓毒症成为一种独特的治疗挑战。延迟或不充分的源头控制是不良预后的独立预测因素，而识别源头控制失败通常较为困难或不可能。在这场争论中，进一步复杂化的问题是源头控制的时机、充分性和程序。本综述评估并总结了当前 IAI 管理的方法和挑战，这也是未来的研究方向。
