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诊断阴道感染:是时候迈入 21 世纪了。

Diagnosing Vaginal Infections: It's Time to Join the 21st Century.

机构信息

Indiana University School of Medicine, 635 North Barnhill, Suite 224, Indianapolis, IN, 46202, USA,

出版信息

Curr Infect Dis Rep. 2010 May;12(3):225-30. doi: 10.1007/s11908-010-0096-1.

DOI:10.1007/s11908-010-0096-1
PMID:21308534
Abstract

Vaginal infections are one of the most common reasons for medical healthcare visits in the United States and Western Europe. These diseases are also significantly associated with HIV acquisition in resource-constrained settings throughout the world. However, despite ample opportunity to improve diagnosis, and therefore management, of vaginitis and vaginosis, the healthcare community continues to rely on diagnostic methods with poor performance characteristics. This state of affairs results in part from the lack of a public health mandate to reduce the burden of these infections in women. Without such a mandate, there is a lack of funding for reimbursement for more sensitive and specific diagnostic assays. Sensitive assays do exist for these infections, and their use should be encouraged when appropriate for clinical care.

摘要

阴道感染是美国和西欧医疗保健就诊的最常见原因之一。在世界各地资源有限的情况下,这些疾病也与艾滋病毒的获得显著相关。然而,尽管有充分的机会改善阴道炎和细菌性阴道病的诊断,从而改善其管理,但医疗保健界仍继续依赖性能特征不佳的诊断方法。这种情况部分是由于缺乏公共卫生任务来减轻这些感染对女性的负担。如果没有这样的任务,就缺乏为更敏感和特异的诊断检测提供报销的资金。这些感染确实存在敏感的检测方法,在适当的临床护理中应鼓励使用。

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本文引用的文献

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Disentangling contributions of reproductive tract infections to HIV acquisition in African Women.解析非洲女性生殖道感染对感染艾滋病毒的影响因素
Sex Transm Dis. 2009 Jun;36(6):357-64. doi: 10.1097/OLQ.0b013e3181a4f695.
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Comparison of APTIMA Trichomonas vaginalis transcription-mediated amplification to wet mount microscopy, culture, and polymerase chain reaction for diagnosis of trichomoniasis in men and women.将APTIMA阴道毛滴虫转录介导扩增法与湿片显微镜检查、培养法及聚合酶链反应用于诊断男性和女性滴虫病的比较。
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Accuracy of the clinical diagnosis of vaginitis compared with a DNA probe laboratory standard.
Aptima 细菌性阴道病和 Aptima 阴道炎检测的临床验证:一项前瞻性多中心临床研究的结果。
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Health care utilization and costs following amplified versus non-amplified molecular probe testing for symptomatic patients with suspected vulvovaginitis: a US commercial payer population.有疑似外阴阴道炎症状的患者进行扩增与非扩增分子探针检测后的医疗保健利用情况及费用:美国商业医保人群
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Chitosan-Based Nanomedicine to Fight Genital Candida Infections: Chitosomes.用于对抗生殖器念珠菌感染的基于壳聚糖的纳米药物:壳聚糖体。
Mar Drugs. 2017 Mar 4;15(3):64. doi: 10.3390/md15030064.
6
Comparison of nucleic acid amplification assays with BD affirm VPIII for diagnosis of vaginitis in symptomatic women.比较核酸扩增检测与 BD affirm VPIII 对有症状女性阴道炎的诊断。
J Clin Microbiol. 2013 Nov;51(11):3694-9. doi: 10.1128/JCM.01537-13. Epub 2013 Aug 28.
与DNA探针实验室标准相比,阴道炎临床诊断的准确性。
Obstet Gynecol. 2009 Jan;113(1):89-95. doi: 10.1097/AOG.0b013e3181909f63.
4
Trichomonas vaginalis treatment reduces vaginal HIV-1 shedding.阴道毛滴虫治疗可减少阴道内HIV-1的脱落。
Sex Transm Dis. 2009 Jan;36(1):11-6. doi: 10.1097/OLQ.0b013e318186decf.
5
Evaluation of the OSOM Trichomonas rapid test versus wet preparation examination for detection of Trichomonas vaginalis vaginitis in specimens from women with a low prevalence of infection.在感染率较低的女性样本中,比较OSOM滴虫快速检测法与湿片镜检法对阴道毛滴虫性阴道炎的检测效果。
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Temporal associations with declining Trichomonas vaginalis diagnosis rates among women in the state of Victoria, Australia, 1947 to 2005.
Sex Transm Dis. 2008 Jun;35(6):572-6. doi: 10.1097/OLQ.0b013e3181666aa3.
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Trichomonas vaginalis infection and human immunodeficiency virus acquisition in African women.非洲女性阴道毛滴虫感染与人类免疫缺陷病毒感染情况
J Infect Dis. 2008 Feb 15;197(4):548-54. doi: 10.1086/526496.
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Factors associated with the prevalence and incidence of Trichomonas vaginalis infection among African American women in New York city who use drugs.纽约市使用毒品的非裔美国女性中阴道毛滴虫感染患病率和发病率的相关因素。
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The prevalence of Trichomonas vaginalis infection among reproductive-age women in the United States, 2001-2004.2001 - 2004年美国育龄妇女阴道毛滴虫感染患病率
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