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Self-adjuvanting multicomponent cancer vaccine candidates combining per-glycosylated MUC1 glycopeptides and the Toll-like receptor 2 agonist Pam3CysSer.

作者信息

Wilkinson Brendan L, Day Stephanie, Malins Lara R, Apostolopoulos Vasso, Payne Richard J

机构信息

School of Chemistry, The University of Sydney, New South Wales 2006, Australia.

出版信息

Angew Chem Int Ed Engl. 2011 Feb 11;50(7):1635-9. doi: 10.1002/anie.201006115. Epub 2011 Jan 7.


DOI:10.1002/anie.201006115
PMID:21308921
Abstract
摘要

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引用本文的文献

[1]
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MedComm (2020). 2024-2-9

[2]
Peptide Hydrogels as Immunomaterials and Their Use in Cancer Immunotherapy Delivery.

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[3]
Development of synthetic, self-adjuvanting, and self-assembling anticancer vaccines based on a minimal saponin adjuvant and the tumor-associated MUC1 antigen.

Chem Sci. 2023-3-1

[4]
From design to clinic: Engineered peptide nanomaterials for cancer immunotherapy.

Front Chem. 2023-1-17

[5]
Peptide-Drug Conjugates: A New Hope for Cancer Management.

Molecules. 2022-10-25

[6]
Injectable DNA Hydrogel-Based Local Drug Delivery and Immunotherapy.

Gels. 2022-6-24

[7]
Precise immunological evaluation rationalizes the design of a self-adjuvanting vaccine composed of glycan antigen, TLR1/2 ligand, and T-helper cell epitope.

RSC Adv. 2022-6-29

[8]
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[9]
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[10]
Fully synthetic Mincle-dependent self-adjuvanting cancer vaccines elicit robust humoral and T cell-dependent immune responses and protect mice from tumor development.

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