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2004 年至 2009 年中国重庆斑贴试验的回顾性研究。

A retrospective study of patch tests in Chongqing, China from 2004 to 2009.

机构信息

Department of Dermatology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.

出版信息

Contact Dermatitis. 2011 Jul;65(1):28-33. doi: 10.1111/j.1600-0536.2010.01854.x. Epub 2011 Feb 10.

Abstract

BACKGROUND

There has been no previous report on allergens responsible for dermatitis in southwest China.

OBJECTIVE

To investigate the prevalence of contact allergy in southwest China, we retrospectively analysed the patch testing results in our department from 2004 to 2009.

METHODS

A total of 2758 patients were patch tested with the Chinese baseline series of contact allergens (Beijing Medical University), the most common baseline series used in China. The results from patch tests were collected, analysed, and compared with clinical findings.

RESULTS

Of 2758 patients tested, 1826 (66.2%) were allergic to one or more common allergens. Five hundred (27.4%) patients had more than two contact allergies. One patient showed positive reactions to seven allergens. The most common allergens among the 1826 patients with positive reactions were nickel sulfate (39.5%), potassium dichromate (13.5%), thiomersal (11.6%), fragrance mix (6.9%), and rubber mix IV (5.8%). Nickel sensitivity was more common in female patients, and potassium dichromate sensitivity was more common in male patients (p < 0.001).

CONCLUSION

Contact allergy in southwest China has particular characteristics, and these findings should be helpful in the development of strategies to reduce contact allergy in this geographical region.

摘要

背景

目前尚无中国西南地区导致接触性皮炎的过敏原的相关报道。

目的

为了调查中国西南地区接触过敏的流行情况,我们回顾性分析了 2004 年至 2009 年我科的斑贴试验结果。

方法

对 2758 例患者进行了中国基础系列接触过敏原斑贴试验(北京医科大学),这是中国最常用的基础系列。收集、分析并比较了斑贴试验结果与临床发现。

结果

在 2758 例接受测试的患者中,1826 例(66.2%)对一种或多种常见过敏原过敏。500 例(27.4%)患者有两种以上的接触过敏。1 例患者对 7 种过敏原呈阳性反应。1826 例阳性反应患者中最常见的过敏原是硫酸镍(39.5%)、重铬酸钾(13.5%)、硫柳汞(11.6%)、香薰混合物(6.9%)和橡胶混合物 IV(5.8%)。女性患者对镍的敏感性更高,而男性患者对重铬酸钾的敏感性更高(p<0.001)。

结论

中国西南地区的接触过敏具有特殊的特征,这些发现有助于制定减少该地区接触过敏的策略。

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