Synthesis of some nucleosides derivatives from L- rhamnose with expected biological activity.
作者信息
Ghoneim Amira Atef
机构信息
Chemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt.
出版信息
Chem Cent J. 2011 Feb 11;5(1):7. doi: 10.1186/1752-153X-5-7.
Abstract
Practical procedures for production of variously blocked compounds from L-rhamnose have been developed. These compounds are highly useful as indirect β-L-rhamnosyl donors. This approach represents a new method for the synthesis of aromatic nucleoside analogues and the synthesis of (3S, 4S, 5S, 6R) 3, 4, 5-triacetoxy-2-methyl-7,9-diaza-1-oxa-spiro [4,5]decane-10-one-8-thione (7).
摘要
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