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[智利的乙型病毒性急性肝炎:临床及发展特征]

[Acute hepatitis by virus B in Chile: clinical and developmental characteristics].

作者信息

Brahm J, Hurtado C, Velasco M

机构信息

Centro de Gastroenterología, Hospital Clínico de la Universidad de Chile, Santiago.

出版信息

Rev Med Chil. 1990 Mar;118(3):264-8.

PMID:2131505
Abstract

We report clinical characteristics and follow up in 31 patients with acute B-hepatitis. Twenty were male and the age ranged from 9 to 80 years (mean 38). The infecting mechanism was probably related to homosexuality in 11, parenteral contact in 4 (1 post transfusional), health care workers in 4, home contact in 3, promiscuity in 3 and unknown in 6. Of 24 patients followed for a mean of 2 years, 20 recovered completely (84%). Anti HBs appeared 2 to 17 months (mean 8.3) after disappearance of HBsAg. Two had fulminant hepatitis and died, 1 developed chronic active hepatitis and 1 with subfulminant disease died after 6.5 months. Thus, the known risk factors for B-Hepatitis are confirmed in this series.

摘要

我们报告了31例急性乙型肝炎患者的临床特征及随访情况。其中20例为男性,年龄在9岁至80岁之间(平均38岁)。感染机制可能与11例同性恋、4例经肠外接触(1例输血后)、4例医护人员、3例家庭接触、3例滥交以及6例情况不明有关。在24例平均随访2年的患者中,20例完全康复(84%)。抗-HBs在HBsAg消失后2至17个月出现(平均8.3个月)。2例发生暴发性肝炎并死亡,1例发展为慢性活动性肝炎,1例亚暴发性肝炎患者在6.5个月后死亡。因此,本系列研究证实了已知的乙型肝炎危险因素。

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