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银屑病关节炎的诊断与治疗进展。

An update on the diagnosis and management of psoriatic arthritis.

机构信息

Department of Dermatology, Medical University of Graz, Graz, Austria.

出版信息

G Ital Dermatol Venereol. 2011 Feb;146(1):1-8.

Abstract

Psoriasis is a common inflammatory disease with complex genetic background affecting approximately 2-3% of the population in the Western hemisphere. Around 20% of psoriasis patients also suffer from psoriatic arthritis (PsA). The clinical spectrum comprises a wide variety of arthritic manifestations ranging from dactylitis, peripheral symmetric or asymmetric mono-, oligo-, and polyarticular arthritis, spinal disease and enthesitis. As psoriasis precedes PsA in 75-80% of affected patients, dermatologists might play a pivotal role in early diagnosis of the disease. Furthermore, magnetic resonance imaging (MRI) scanning and ultrasonography have improved the radiological diagnosis of peripheral PsA, psoriatic spondylarthropathy and enthesitis. Besides the traditional treatment of PsA the introduction of biologics has led to a significant improvement in the treatment of the disease. To further improve diagnosis, treatment and quality of life in our patients suffering from PsA an excellent interdisciplinary collaboration between dermatologists, radiologists and rheumatologists is a necessity of utmost importance.

摘要

银屑病是一种常见的炎症性疾病,具有复杂的遗传背景,影响大约 2-3%的西半球人口。大约 20%的银屑病患者也患有银屑病关节炎(PsA)。其临床表现包括多种多样的关节炎表现,从指(趾)炎、外周对称性或不对称性单、寡、多关节炎、脊柱疾病和附着点炎。由于银屑病在 75-80%的受累患者中先于 PsA 发生,皮肤科医生可能在疾病的早期诊断中发挥关键作用。此外,磁共振成像(MRI)扫描和超声检查提高了外周型 PsA、银屑病性脊柱关节炎和附着点炎的放射学诊断。除了传统的 PsA 治疗方法外,生物制剂的引入也显著改善了该病的治疗效果。为了进一步提高我们的银屑病关节炎患者的诊断、治疗和生活质量,皮肤科医生、放射科医生和风湿病医生之间的卓越跨学科合作是至关重要的。

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