Department of Rheumatology, P. D. Hinduja National Hospital, Mahim, Mumbai, India.
Indian J Dermatol Venereol Leprol. 2013 Jul;79 Suppl 7:S18-24. doi: 10.4103/0378-6323.115507.
Psoriatic arthritis (PsA) is a multi-faceted disease marked by varying combinations of peripheral arthritis, dactylitis, spondylitis, and enthesitis. Rarely, recurrent uveitis occurs. Skin involvement may or may not exist. However, patients with nail psoriasis have a higher probability of developing PsA. Untreated patients have significant morbidity and mortality. Timely diagnosis and aggressive treatment of the disease can lead to lower morbidity. Drug therapy of PsA includes symptomatic therapy and therapy with disease-modifying anti-rheumatic drugs. Biologics are the only agents that address all the pathological changes, of this chronic condition.
银屑病关节炎（PsA）是一种多方面的疾病，其特征是外周关节炎、指（趾）炎、脊椎炎和肌腱端炎的不同组合。很少有复发性虹膜炎。皮肤受累可能存在也可能不存在。然而，患有指甲银屑病的患者更有可能发展为 PsA。未经治疗的患者有较高的发病率和死亡率。及时诊断和积极治疗疾病可降低发病率。PsA 的药物治疗包括对症治疗和疾病修饰抗风湿药物治疗。生物制剂是唯一能解决这种慢性疾病所有病理变化的药物。
