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涉及抗胆碱酯酶化合物的大规模伤亡事件评估与管理的准备情况:对美国12个最大城市急诊科主任的调查

Preparedness for the evaluation and management of mass casualty incidents involving anticholinesterase compounds: a survey of emergency department directors in the 12 largest cities in the United States.

作者信息

Madsen James M, Greenberg Michael I

机构信息

Chemical Casualty Care Division, U.S. Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, Maryland, USA.

出版信息

Am J Disaster Med. 2010 Nov-Dec;5(6):333-51.

PMID:21319552
Abstract

OBJECTIVES

Anticholinesterases include carbamate and organophosphorus (OP) insecticides and nerve agents. Release of these compounds can flood emergency departments (EDs) with large numbers of poisoned victims and worried individuals. It was hypothesized that despite the focus of disaster preparedness on large metropolitan areas, EDs in these cities would still report self-perceptions of deficiencies in preparedness for mass casualty incidents (MCIs) involving these chemicals.

DESIGN AND SETTING

A secure and anonymous online survey was prepared and piloted, and E-mail invitations were sent to the physician directors of the 220 continuously staffed EDs in the 12 most populous incorporated cities in the United States.

RESULTS

Forty-six ED directors could not be contacted despite repeated attempts. Of the remaining 174 directors, eight declined and 89 took the survey, for a response rate of 51.1 percent. Fewer than 20 percent were very confident in the effectiveness of their training, and only 4.9 percent were very confident that drills had given them the preparation that they needed. Only 45. 7 percent of reporting hospitals had a board-certified medical toxicologist to help in such an emergency. Almost two-thirds (73.6 percent) of those familiar with the online Radiation Event Medical Management (REMM) module from the National Library of Medicine and the National Institutes of Health thought that a chemical counterpart to REMM would be either moderately or very helpful for MCIs involving anticholinesterases.

CONCLUSIONS

This study demonstrates that physician ED directors perceived marked deficiencies in their abilities to respond to this kind of toxicological emergency and suggests critical directions for remediation of these deficiencies.

摘要

目的

抗胆碱酯酶剂包括氨基甲酸酯类和有机磷杀虫剂及神经毒剂。这些化合物的泄漏会使大量中毒患者和焦虑的人群涌入急诊科。据推测,尽管灾难准备工作主要集中在大城市地区,但这些城市的急诊科仍会报告称,他们认为在应对涉及这些化学品的大规模伤亡事件(MCI)时准备不足。

设计与背景

准备并试运行了一项安全且匿名的在线调查,并向美国人口最多的12个建制市中220个持续配备工作人员的急诊科的主任医生发送了电子邮件邀请。

结果

尽管多次尝试,仍有46位急诊科主任无法取得联系。在其余174位主任中,8位拒绝参与,89位参与了调查,回复率为51.1%。不到20%的人对其培训效果非常有信心,只有4.9%的人非常确信演练使他们获得了所需的准备。报告的医院中只有45.7%拥有经委员会认证的医学毒理学家来协助应对此类紧急情况。在熟悉美国国立医学图书馆和美国国立卫生研究院的在线辐射事件医疗管理(REMM)模块的人中,近三分之二(73.6%)认为,REMM的化学对应模块对涉及抗胆碱酯酶剂的大规模伤亡事件会有一定帮助或非常有帮助。

结论

本研究表明,急诊科主任医生认为他们应对此类毒理学紧急情况的能力存在明显不足,并提出了弥补这些不足的关键方向。

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