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躯干性发作癫痫的代谢成像关联

Metabolic imaging correlate of truncal onset seizures.

作者信息

Oster Joel M, Aljumairi Fajer, Cosgrove G Rees

机构信息

Neurology Department 7W, Lahey Clinic, 41 Mall Rd, Burlington, MA 01805, USA.

出版信息

Arch Neurol. 2011 Feb;68(2):251-3. doi: 10.1001/archneurol.2010.370.

Abstract

OBJECTIVE

To denote the metabolic imaging localization of seizure onset with ictal and interictal Neurolite single-photon emission computed tomographic scans and difference images made by subtracting activity at individual voxels of these images, which ultimately identify intense focal uptake in the trunk motor region and other, probably secondarily, propagated pathways.

DESIGN

Retrospective review of a unique case report.

SETTING

A suburban epilepsy referral center.

PATIENT

A 59-year-old man with truncal-onset seizure.

INTERVENTIONS

Ictal and interictal metabolic imaging.

MAIN OUTCOME MEASURES

Onset location of ictal events.

RESULTS

The patient had a gliotic lesion in a focal region on magnetic resonance imaging undercutting the trunk motor area in the cortex of the precentral gyrus with concordant single-photon emission computed tomographic imaging.

CONCLUSIONS

While truncal-onset seizures have been described previously in a few case reports, they are clinically rare. As far as we know, this is the only case report in the literature in which metabolic imaging was carried out with this entity and is consistent with the anatomical localization of seizure onset in the trunk motor area.

摘要

目的

通过发作期和发作间期的Neurolite单光子发射计算机断层扫描以及通过减去这些图像中各个体素的活性所制成的差值图像,来确定癫痫发作起始的代谢成像定位,最终识别躯干运动区域以及其他可能继发的传播途径中的强烈局灶性摄取。

设计

对一份独特病例报告的回顾性研究。

地点

一个郊区癫痫转诊中心。

患者

一名59岁的躯干发作性癫痫男性患者。

干预措施

发作期和发作间期的代谢成像。

主要观察指标

发作期事件的起始位置。

结果

该患者在磁共振成像上的一个局灶区域存在胶质增生性病变,该区域位于中央前回皮质的躯干运动区下方,单光子发射计算机断层成像结果与之相符。

结论

虽然之前在少数病例报告中描述过躯干发作性癫痫,但临床上较为罕见。据我们所知,这是文献中唯一一篇对该病例进行代谢成像的报告,且与躯干运动区癫痫发作起始的解剖定位一致。

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