一种纳米级 DNA-Au 树状聚合物作为信号放大器，用于通用设计基于功能 DNA 的 SERS 生物传感器。
A nanoscale DNA-Au dendrimer as a signal amplifier for the universal design of functional DNA-based SERS biosensors.
机构信息
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China.
出版信息
Chem Commun (Camb). 2011 Apr 7;47(13):3840-2. doi: 10.1039/c0cc05133k. Epub 2011 Feb 14.
PMID:21321698
Abstract
The use of a nanoscale DNA-Au dendrimer as a signal amplifier was proposed for the universal design of functional DNA-based ultra-sensitive SERS biosensors. This novel design combines the high specificity of functional DNA with the high sensitivity of surface-enhanced Raman scattering (SERS) spectroscopy, resulting in sensitivity superior to that of previously reported sensors.
摘要
纳米尺度的 DNA-Au 树状大分子被用作信号放大器，用于基于功能 DNA 的超灵敏 SERS 生物传感器的通用设计。这种新颖的设计将功能 DNA 的高特异性与表面增强拉曼散射 (SERS) 光谱的高灵敏度相结合，使得灵敏度优于以前报道的传感器。
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