组合合成三苯基甲烷文库及其在表面增强拉曼散射（SERS）探针开发中的应用。
Combinatorial synthesis of a triphenylmethine library and their application in the development of surface enhanced Raman scattering (SERS) probes.
机构信息
Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), 11 Biopolis Way, Singapore 138667.
出版信息
Chem Commun (Camb). 2010 Feb 7;46(5):722-4. doi: 10.1039/b921550f. Epub 2009 Dec 17.
The first synthesis of a triphenylmethine (TM) library of compounds and screening of their Surface Enhanced Raman Scattering (SERS) capability was carried out to identify novel Raman reporters with high sensitivity. We identified three novel SERS reporters (B2, B7, and C7) with higher signal intensity than that of commonly used crystal violet (CV). These reporters may find potential applications in developing sensitive SERS based biosensors.
首次合成了三苯甲烷（TM）化合物库，并对其表面增强拉曼散射（SERS）性能进行了筛选，以鉴定具有高灵敏度的新型拉曼报告分子。我们鉴定了三个新型 SERS 报告分子（B2、B7 和 C7），其信号强度高于常用的结晶紫（CV）。这些报告分子可能在开发基于 SERS 的敏感生物传感器方面具有潜在应用。
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