用于铅离子检测的 SERS DNAzyme 生物传感器。
A SERS DNAzyme biosensor for lead ion detection.
机构信息
Bindley Bioscience Center and Birck Nanotechnology Center, Purdue University 225 S, University Street, 215 ABE Building, West Lafayette, IN 47907, USA.
出版信息
Chem Commun (Camb). 2011 Apr 21;47(15):4394-6. doi: 10.1039/c0cc04140h. Epub 2011 Mar 9.
PMID:21387077
Abstract
SERS biosensor for sensitive and selective detection of lead ions (Pb(2+)) based on DNAzyme was developed by taking advantage of the specific catalytic reaction of DNAzyme upon binding to Pb(2+) ions. Detection was accomplished by SERS nanoprobe labeled with DNA and Raman reporters for signal amplification.
摘要
基于 DNAzyme 对 Pb(2+) 离子结合的特异性催化反应，开发了用于灵敏和选择性检测 Pb(2+) 离子的 SERS 生物传感器。通过标记有 DNA 和拉曼报告分子的 SERS 纳米探针进行信号放大来实现检测。
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