Hickman P E, Potter J M
Department of Biochemistry, Royal Perth Hospital, WA.
Aust N Z J Med. 1990 Feb;20(1):32-4. doi: 10.1111/j.1445-5994.1990.tb00366.x.
Twenty-nine patients of 18,000 inpatient admissions over a six-month period developed ischaemic hepatitis accompanied by peak aspartate aminotransferase (AST-EC 2.6.1.1) activity greater than 1,000 U/L. Seventeen of these 29 patients died either during or shortly after the episode of ischaemic hepatitis, with an overall mortality of 58.6%. Mortality was not due in any of the cases to the hepatitis but rather the underlying cause. Ischaemic hepatitis was the commonest cause of an AST activity greater than 1,000 U/L in this hospital population (29 of 52 patients i.e. 56%). This condition is more common than generally appreciated and is associated with a poor prognosis.
在六个月的时间里，18000例住院患者中有29例发生了缺血性肝炎，同时天冬氨酸转氨酶（AST-EC 2.6.1.1）的峰值活性超过1000 U/L。这29例患者中有17例在缺血性肝炎发作期间或之后不久死亡，总死亡率为58.6%。所有病例的死亡均非由肝炎所致，而是由潜在病因引起。在该医院人群中，缺血性肝炎是AST活性超过1000 U/L的最常见原因（52例患者中有29例，即56%）。这种情况比普遍认为的更为常见，且预后较差。
