Department of Primary Health Care, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Scand J Prim Health Care. 2011 Mar;29(1):51-6. doi: 10.3109/02813432.2011.554011.
Using validated screening instruments to detect depressive symptoms in the elderly has been recommended. The aim of this study was to compare a patient-centred consultation model with the PRIME-MD screening questionnaire, using the MADRS-S as reference for detecting depressive symptoms in an elderly primary care population.
Comparative study.
Primary care, Sweden.
During an 11-month period 302 consecutive patients aged 60 and over attending a primary care centre were screened with the PRIME-MD and the Montgomery-Asberg Depression Rating Scale-Self-rated version (MADRS-S) instrument. The results were unknown to the GPs who used a structured, patient-centred consultation model comprising seven open-ended "key questions".
Sensitivity, specificity, positive predictive values (PPV), and negative predictive values (NPV) were calculated for the PRIME-MD screening questionnaire and the patient-centred consultation model using MADRS-S as reference for possible depression at two cut-off levels with 15% prevalence. Results. Sensitivity was lower for the consultation model than the PRIME-MD screening questionnaire: 78% and 98%, respectively. The GPs failed to identify every fifth patient using the lower cut-off (MADRS-S≥13) but the number of required diagnostic interviews decreased by almost 50%: 85 versus 162, respectively. PPV was 43% and 28%, respectively. Both instruments showed high sensitivity (93%) using the higher cut-off (MADRS-S≥20) and had high NPV: 95% and 99%, respectively.
The findings suggest that the consultation screening procedure might be as useful in everyday practice as the PRIME-MD screening questionnaire. Both screening procedures may also be useful for ruling out depressive symptoms.
建议使用经过验证的筛选工具来检测老年人的抑郁症状。本研究旨在比较以患者为中心的咨询模式与 PRIME-MD 筛查问卷,使用 MADRS-S 作为参考标准,以检测老年初级保健人群中的抑郁症状。
比较研究。
瑞典初级保健。
在为期 11 个月的时间里,连续 302 名年龄在 60 岁及以上的患者在初级保健中心接受了 PRIME-MD 和蒙哥马利-阿斯伯格抑郁评定量表自评版(MADRS-S)的筛查。全科医生在进行评估时并不知道这些结果,他们使用了一种结构化的、以患者为中心的咨询模式,包括七个开放式“关键问题”。
使用 MADRS-S 作为可能抑郁的参考标准,计算 PRIME-MD 筛查问卷和以患者为中心的咨询模式的敏感性、特异性、阳性预测值(PPV)和阴性预测值(NPV),采用 15%的患病率和两个截止值。结果:咨询模式的敏感性低于 PRIME-MD 筛查问卷,分别为 78%和 98%。使用较低的截止值(MADRS-S≥13),医生无法识别每五个患者中的一个,但所需的诊断性访谈数量减少了近 50%:分别为 85 次和 162 次。PPV 分别为 43%和 28%。两个工具在使用较高截止值(MADRS-S≥20)时均具有高敏感性(93%),且 NPV 较高:分别为 95%和 99%。
研究结果表明,咨询筛查程序在日常实践中可能与 PRIME-MD 筛查问卷一样有用。这两种筛查方法也可用于排除抑郁症状。