Wikberg Carl, Nejati Shabnam, Larsson Maria E H, Petersson Eva-Lisa, Westman Jeanette, Ariai Nashmil, Kivi Marie, Eriksson Maria, Eggertsen Robert, Hange Dominique, Baigi Amir, Björkelund Cecilia
Department of Primary Health Care, Institute of Medicine (Drs Petersson, Eggertsen, Hange, Baigi, and Björkelund; Mr Wikberg; and Mss Nejati, Ariai, and Eriksson), Department of Clinical Neuroscience and Rehabilitation, Institute of Neuroscience and Physiology (Dr Larsson), and Department of Psychology (Ms Kivi), University of Gothenburg, Gothenburg, Sweden; Närhälsan Research and Development Primary Health Care, Region Västra Götaland, Gothenburg, Sweden (Drs Larsson and Petersson); and Department of Neurobiology, Care Sciences and Society, Center for Family Medicine, Karolinska Institutet, Stockholm, Sweden (Dr Westman).
Prim Care Companion CNS Disord. 2015 Jun 25;17(3). doi: 10.4088/PCC.14m01758. eCollection 2015.
The Montgomery-Asberg Depression Rating Scale-Self (MADRS-S) and the Beck Depression Inventory II (BDI-II) are commonly used self-assessment instruments for screening and diagnosis of depression. The BDI-II has 21 items and the MADRS-S has 9 items. These instruments have been tested with psychiatric inpatients but not in outpatient primary care, where most patients with symptoms of depression initially seek treatment. The purpose of this study was to compare these 2 instruments in the primary care setting.
Data were collected from 2 primary care randomized controlled trials that were performed from 2010 to 2013 in Sweden: the Primary Care Self-Assessment MADRS-S Study and Primary Care Internet-Based Cognitive Behavioral Therapy Study. There were 146 patients (73 patients each from both trials) who had newly diagnosed mild or moderate depression (per DSM-IV recommendations) and who had assessment with both the MADRS-S and BDI-II at primary care centers. Comparability and reliability of the instruments were estimated by Pearson product moment correlation and Cronbach α.
A good correlation was observed between the 2 instruments: 0.66 and 0.62 in the 2 study cohorts. The reliability within the 2 study cohorts was good for both MADRS-S (Cronbach α: 0.76 for both cohorts) and BDI-II items (Cronbach α: 0.88 and 0.85).
The 2 instruments showed good comparability and reliability for low, middle, and high total depression scores. The MADRS-S may be used as a rapid, easily administered, and inexpensive tool in primary care and has results comparable to the BDI-II in all domains.
蒙哥马利-奥斯伯格抑郁评定量表-自评版(MADRS-S)和贝克抑郁量表第二版(BDI-II)是常用于抑郁症筛查和诊断的自评工具。BDI-II有21个条目,MADRS-S有9个条目。这些工具已在精神科住院患者中进行了测试,但未在门诊初级保健中进行测试,而大多数有抑郁症状的患者最初会在门诊初级保健中寻求治疗。本研究的目的是在初级保健环境中比较这两种工具。
数据收集自2010年至2013年在瑞典进行的2项初级保健随机对照试验:初级保健自评MADRS-S研究和基于互联网的初级保健认知行为疗法研究。有146名患者(两项试验各73名)新诊断为轻度或中度抑郁症(根据《精神疾病诊断与统计手册》第四版的建议),并在初级保健中心接受了MADRS-S和BDI-II评估。通过皮尔逊积差相关和克朗巴赫α系数估计工具的可比性和信度。
在两个研究队列中观察到这两种工具之间有良好的相关性:分别为0.66和0.62。两个研究队列中,MADRS-S(两个队列的克朗巴赫α系数均为0.76)和BDI-II条目(克朗巴赫α系数分别为0.88和0.85)的信度都很好。
这两种工具在低、中、高抑郁总分上显示出良好的可比性和信度。MADRS-S可作为初级保健中一种快速、易于实施且成本低廉的工具,在所有领域的结果与BDI-II相当。